Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL2857743 | 0.83 | KMT2A (0.70) | ALDH1A1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL2857744 | 0.77 | KMT2A (0.70) | ALDH1A1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL6527378 | 0.74 | KMT2A (0.62) | ALDH1A1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL27949437 | 0.74 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL16244880 | 0.73 | ALDH1A1 (0.74) | ALDH1A1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL27600510 | 0.73 | ALDH1A1 (0.57) | ALDH1A1KMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL21496376 | 0.72 | ALDH1A1 (0.82) | ALDH1A1KMT2AMEN1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL21494140 | 0.72 | ALDH1A1 (0.80) | ALDH1A1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL14158941 | 0.70 | KMT2A (1.00) | ALDH1A1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL6524004 | 0.68 | KMT2A (0.60) | ALDH1A1KMT2AMEN1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2213660-B1 | 5-SUBSTITUTED INDOL-3-CARBOXYLIC ACID DERIVATIVES EXHIBITING ANTIVIRAL ACTIVITY A METHOD FOR THE PRODUCTION AND USE THEREOF | RES AND DEV COMPANY MEDBIOPHARM LTD (RU) | 2012-12-12 | — | — | EP | disclosed |
| US-20110065919-A1 | 5-Substituted Indol-3-Carboxylic Acid Derivatives Exhibiting Antiviral Activity a Method for the Production and Use Thereof | OOO "BINATEKH" (RU) | 2011-03-17 | — | — | US | disclosed |
| EP-2213660-A1 | 5-SUBSTITUTED INDOL-3-CARBOXYLIC ACID DERIVATIVES EXHIBITING ANTIVIRAL ACTIVITY A METHOD FOR THE PRODUCTION AND USE THEREOF | Obschestvo S Ogranichennoy Otvetstvennostju "Binatekh" (RU) | 2010-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065919-A1 | 5-Substituted Indol-3-Carboxylic Acid Derivatives Exhibiting Antiviral Activity a Method for the Production and Use Thereof | CBR3, IFNAR1, SIGMAR1 | ALDH1A1 2627/4885KMT2A 4466/4885MEN1 4185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.