Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.53 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.52 |
| ▸ | MLNR | O43193 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857744 | 0.88 | KMT2A (0.70) | KMT2AALDH1A1MEN1SMN1; SMN2KDM4E | |
| SCHEMBL2864474 | 0.83 | ALDH1A1 (0.61) | KMT2AALDH1A1MEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL27600510 | 0.81 | ALDH1A1 (0.57) | KMT2AALDH1A1MEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL21496376 | 0.79 | ALDH1A1 (0.82) | KMT2AALDH1A1MEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL28726997 | 0.78 | KMT2A (0.69) | KMT2AALDH1A1MEN1SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL21494140 | 0.78 | ALDH1A1 (0.80) | KMT2AALDH1A1MEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6527378 | 0.78 | KMT2A (0.62) | KMT2AALDH1A1MEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4445035 | 0.76 | ALOX5 (0.74) | KMT2AALDH1A1MEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL31693208 | 0.74 | L3MBTL1 (0.59) | KMT2AALDH1A1MEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6524004 | 0.74 | KMT2A (0.60) | KMT2AALDH1A1MEN1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2213660-A1 | 5-SUBSTITUTED INDOL-3-CARBOXYLIC ACID DERIVATIVES EXHIBITING ANTIVIRAL ACTIVITY A METHOD FOR THE PRODUCTION AND USE THEREOF | Obschestvo S Ogranichennoy Otvetstvennostju "Binatekh" (RU) | 2010-08-04 | — | — | EP | disclosed |