Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ASPH | Q12797 | 5/20 | 0.34 |
| ▸ | KDM8 | Q8N371 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | AGER | Q15109 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566964 | 0.77 | KDM4E (0.41) | KDM4EALOX15L3MBTL1ALDH1A1ASPH | |
| SCHEMBL19181538 | 0.69 | RAF1 (0.33) | ALDH1A1GAACYP1A2CYP3A4TSHR | |
| SCHEMBL19181539 | 0.69 | RAF1 (0.33) | ALDH1A1GAACYP1A2CYP3A4TSHR | |
| SCHEMBL7199668 | 0.67 | KDM4E (0.47) | KDM4EALOX15L3MBTL1ALDH1A1ASPH | |
| SCHEMBL25202874 | 0.67 | P2RX3 (0.33) | KDM4EALDH1A1CYP1A2 | |
| SCHEMBL25184605 | 0.67 | P2RX3 (0.33) | KDM4EALDH1A1CYP1A2 | |
| SCHEMBL31376772 | 0.67 | KDM4E (0.34) | KDM4EKMT2AMAPTCYP2C19 | |
| SCHEMBL15942322 | 0.66 | HPGD (0.33) | LMNA | |
| SCHEMBL29987434 | 0.66 | BRD4 (0.41) | KDM4EALOX15L3MBTL1ALDH1A1GAA | |
| SCHEMBL9684174 | 0.66 | KDM4E (0.50) | KDM4EALOX15L3MBTL1ALDH1A1ASPH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113316568-A | 2-formyl-3-hydroxyphenyloxymethyl compounds capable of modulating hemoglobin | 全球血液疗法股份有限公司 | 2021-08-27 | — | — | CN | disclosed |