Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.34 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.34 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20132284 | 0.81 | CYP17A1 (0.45) | CYP17A1MAPK14KDM4EKMT2AALDH1A1 | |
| SCHEMBL13345457 | 0.76 | PPARG (0.40) | CYP17A1KMT2AALDH1A1PPARGPPARA | |
| SCHEMBL29768878 | 0.74 | CYP17A1 (0.51) | CYP17A1MAPK14PPARGMMP1MMP2 | |
| SCHEMBL20132103 | 0.74 | CYP17A1 (0.51) | CYP17A1MAPK14PPARGMMP1MMP2 | |
| SCHEMBL20748365 | 0.73 | KDM4E (0.52) | KDM4EKMT2AALDH1A1MMP1MMP2 | |
| SCHEMBL31359170 | 0.71 | KDM4E (0.44) | KDM4EKMT2AALDH1A1CYP2C9NPC1 | |
| SCHEMBL6162530 | 0.71 | CA12 (0.38) | CYP17A1KDM4E | |
| SCHEMBL24622540 | 0.70 | CYP17A1 (0.44) | CYP17A1MAPK14KDM4ENPC1RECQL | |
| SCHEMBL6478595 | 0.70 | HPGD (0.44) | CYP17A1KDM4EALDH1A1KCNQ4KCNQ5 | |
| SCHEMBL25128919 | 0.69 | CYP17A1 (0.57) | CYP17A1MAPK14DRD2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220354959-A1 | GLUCOCORTICOID RECEPTOR AGONIST AND IMMUNOCONJUGATES THEREOF | ABBVIE INC. (US) | 2022-11-10 | — | — | US | disclosed |
| CN-109476699-B | Glucocorticoid receptor agonists and immunoconjugates thereof | 艾伯维公司 | 2021-10-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220354959-A1 | GLUCOCORTICOID RECEPTOR AGONIST AND IMMUNOCONJUGATES THEREOF | NR3C1, NR3C2, MC2R | CYP17A1 256/4885MAPK14 1917/4885DRD2 1692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.