SCHEMBL28645302

SCHEMBL28645302

Cc1c(N(C)C=O)cc(F)cc1N(C)c1cccc(F)c1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.36
ACHE P22303 1/20 0.33
KMT2A Q03164 3/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
DHODH Q02127 1/20 0.31
F2 P00734 1/20 0.31
F10 P00742 1/20 0.31
TAAR1 Q96RJ0 1/20 0.30
NFE2L2 Q16236 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
GPBAR1 Q8TDU6 1/20 0.30
MEN1 O00255 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28925354 0.78 HSD17B1 (0.34) ACHE
SCHEMBL2089356 0.78 ACHE (0.40) ABCG2ACHEKMT2ANPC1RAB9A
SCHEMBL29454066 0.78 ABCG2 (0.38) ABCG2ACHEKMT2ANPC1RAB9A
SCHEMBL22232350 0.78 ABCG2 (0.38) ABCG2ACHEKMT2ANPC1RAB9A
SCHEMBL31723221 0.78 ABCG2 (0.38) ABCG2ACHEKMT2ANPC1RAB9A
SCHEMBL28645304 0.73 GAA (0.38) ABCG2KMT2ANPC1RAB9ADHODH
SCHEMBL22231705 0.70 ABCG2 (0.32) ABCG2ALDH1A1
SCHEMBL22231704 0.70 ABCG2 (0.32) ABCG2ALDH1A1
SCHEMBL22231907 0.69 ABCG2 (0.36) ABCG2ACHEKMT2AF2F10
SCHEMBL31723238 0.69 ABCG2 (0.36) ABCG2ACHEKMT2AF2F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113454063-A 3-substituted phenylamidine compounds, preparation method and application thereof PI工业有限公司 2021-09-28 CN claimed