SCHEMBL28925354

SCHEMBL28925354

Cc1cccc(F)c1N(C)c1cc(F)cc(N(C)C=O)c1C

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 1/20 0.34
HSD17B2 P37059 1/20 0.34
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22231985 0.80 HSD17B1 (0.34) HSD17B1HSD17B2ACHE
SCHEMBL31723224 0.80 HSD17B1 (0.34) HSD17B1HSD17B2ACHE
SCHEMBL29454101 0.80 HSD17B1 (0.34) HSD17B1HSD17B2ACHE
SCHEMBL28645302 0.78 ABCG2 (0.36) ACHE
SCHEMBL22232486 0.72 NPC1 (0.30)
SCHEMBL22232483 0.72 NPC1 (0.30)
SCHEMBL2093022 0.71 HSD17B1 (0.39) HSD17B1HSD17B2ACHE
SCHEMBL28642936 0.70 TAAR1 (0.36)
SCHEMBL2093944 0.70 TDP1 (0.40) HSD17B1HSD17B2ACHE
SCHEMBL28639761 0.68 MPO (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113454063-A 3-substituted phenylamidine compounds, preparation method and application thereof PI工业有限公司 2021-09-28 CN claimed