Tyramine

Tyramine

SCHEMBL28645404

NCCc1ccc(O)cc1.c1ccccc1

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 9/20 0.90
KDM4E B2RXH2 2/20 0.90
ALDH1A1 P00352 2/20 0.90
HTR1A P08908 2/20 0.90
ADRA2A P08913 2/20 0.90
SLC6A2 P23975 2/20 0.90
BACE1 P56817 2/20 0.90
CYP2C19 P33261 1/20 0.90
HTR3A P46098 1/20 0.90
L3MBTL1 Q9Y468 1/20 0.90
TDP1 Q9NUW8 2/20 0.86
BLM P54132 1/20 0.86
KMT2A Q03164 1/20 0.86
HTR2A P28223 3/20 0.64
CYP2A6 P11509 2/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
LOXL2 Q9Y4K0 1/20 0.64
ESR1 P03372 1/20 0.62
ESR2 Q92731 1/20 0.62
ABAT P80404 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyramine SCHEMBL5898804 0.97 TAAR1 (0.95) TAAR1KDM4EALDH1A1HTR1AADRA2A
Tyramine SCHEMBL10006913 0.95 TAAR1 (0.82) TAAR1KDM4EALDH1A1HTR1AADRA2A
Tyramine SCHEMBL6137697 0.95 TAAR1 (0.82) TAAR1KDM4EALDH1A1HTR1AADRA2A
Tyramine SCHEMBL30831107 0.95 TAAR1 (1.00) TAAR1KDM4EALDH1A1HTR1AADRA2A
Tyramine SCHEMBL134515 0.95 TAAR1 (1.00) TAAR1KDM4EALDH1A1HTR1AADRA2A
Tyramine SCHEMBL4111 0.95 TAAR1 (1.00) TAAR1KDM4EALDH1A1HTR1AADRA2A
Tyramine SCHEMBL30831130 0.95 TAAR1 (1.00) TAAR1KDM4EALDH1A1HTR1AADRA2A
Tyramine SCHEMBL1804993 0.92 TAAR1 (0.95) TAAR1KDM4EALDH1A1HTR1AADRA2A
Tyramine SCHEMBL3950268 0.92 TAAR1 (0.95) TAAR1KDM4EALDH1A1HTR1AADRA2A
Tyramine SCHEMBL7742928 0.92 TAAR1 (0.95) TAAR1KDM4EALDH1A1HTR1AADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113388044-A Snail glycosaminoglycan compound, pharmaceutically acceptable salt thereof, preparation method and application 中国科学院昆明植物研究所 2021-09-14 CN disclosed