Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.95 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.95 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.95 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.95 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.95 |
| ▸ | HTR1A | P08908 | 2/20 | 0.95 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.95 |
| ▸ | HTR3A | P46098 | 1/20 | 0.95 |
| ▸ | BACE1 | P56817 | 1/20 | 0.95 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.95 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.90 |
| ▸ | BLM | P54132 | 2/20 | 0.90 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.90 |
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 3/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.59 |
| ▸ | ABAT | P80404 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyramine SCHEMBL28645404 | 0.97 | TAAR1 (0.90) | TAAR1KDM4EADRA2ASLC6A2ALDH1A1 | |
| Tyramine SCHEMBL134515 | 0.97 | TAAR1 (1.00) | TAAR1KDM4EADRA2ASLC6A2ALDH1A1 | |
| Tyramine SCHEMBL30831130 | 0.97 | TAAR1 (1.00) | TAAR1KDM4EADRA2ASLC6A2ALDH1A1 | |
| Tyramine SCHEMBL30831107 | 0.97 | TAAR1 (1.00) | TAAR1KDM4EADRA2ASLC6A2ALDH1A1 | |
| Tyramine SCHEMBL4111 | 0.97 | TAAR1 (1.00) | TAAR1KDM4EADRA2ASLC6A2ALDH1A1 | |
| Tyramine SCHEMBL32663617 | 0.95 | TDP1 (1.00) | TAAR1KDM4EADRA2ASLC6A2ALDH1A1 | |
| Tyramine SCHEMBL31738431 | 0.95 | TAAR1 (0.95) | TAAR1KDM4EADRA2ASLC6A2ALDH1A1 | |
| Tyramine SCHEMBL7742928 | 0.95 | TAAR1 (0.95) | TAAR1KDM4EADRA2ASLC6A2ALDH1A1 | |
| Tyramine SCHEMBL3950268 | 0.95 | TAAR1 (0.95) | TAAR1KDM4EADRA2ASLC6A2ALDH1A1 | |
| Tyramine SCHEMBL2574990 | 0.95 | TAAR1 (0.95) | TAAR1KDM4EADRA2ASLC6A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7138241-B2 | Hybridoma, an antibody resistant to an interfering substance, and a kit for immunological analysis | JAPAN ENVIROCHEMICALS, LTD. (JP) | 2006-11-21 | — | — | US | disclosed |
| US-20030064389-A1 | Method of selecting an antibody, a hybridoma, a monoclonal antibody and use thereof | JAPAN ENVIROCHEMICALS, LTD. (JP) | 2003-04-03 | — | — | US | disclosed |
| EP-1258729-A2 | A method of selecting an antibody, a hybridoma, a monoclonal antibody and use thereof | Takeda Chemical Industries, Ltd. (JP) | 2002-11-20 | — | — | EP | disclosed |