Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.56 |
| ▸ | ABAT | P80404 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | FDPS | P14324 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.48 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.48 |
| ▸ | TACR2 | P21452 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24723792 | 0.91 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2MAPTTRIM24HPGD | |
| SCHEMBL28645184 | 0.90 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL28927694 | 0.87 | TACR2 (0.64) | ALDH1A1SMN1; SMN2MAPTHPGDTDP1 | |
| SCHEMBL4855402 | 0.84 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2MAPTTRIM24HPGD | |
| SCHEMBL31054299 | 0.83 | FDPS (0.75) | ALDH1A1SMN1; SMN2MAPTHPGDMEN1 | |
| SCHEMBL2850023 | 0.83 | FDPS (0.75) | ALDH1A1SMN1; SMN2MAPTHPGDMEN1 | |
| SCHEMBL14554263 | 0.82 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2MAPTTRIM24HPGD | |
| SCHEMBL15096645 | 0.80 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2MAPTTRIM24HPGD | |
| SCHEMBL25268335 | 0.79 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2MAPTTRIM24HPGD | |
| SCHEMBL3394561 | 0.77 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2MAPTTRIM24HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110294732-B | Pharmaceutical compound for treating liver diseases and application thereof | 江苏新元素医药科技有限公司 | 2021-10-26 | — | — | CN | disclosed |