SCHEMBL2864544

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2860775	0.78	KDM4E (0.51)	CES2CES1PARP1HDAC1HDAC6
	SCHEMBL1513045	0.77	CES2 (0.57)	CES2CES1PARP1HDAC1HDAC6
	SCHEMBL29084385	0.75	CES2 (0.50)	CES2CES1PARP1HDAC1HDAC6
	SCHEMBL1258944	0.74	CES2 (0.74)	CES2CES1PARP1HDAC1HDAC6
	SCHEMBL2863967	0.74	KMT2A (0.53)	CES2CES1HDAC1HDAC6KMT2A
	SCHEMBL1715824	0.73	ALDH1A1 (0.47)	CES2CES1UNGNFE2L2NPC1
	Hydrochloric Acid SCHEMBL27733562	0.72	CES2 (0.71)	CES2CES1PARP1HDAC1HDAC6
	SCHEMBL2705684	0.72	CES2 (0.71)	CES2CES1PARP1HDAC1HDAC6
	SCHEMBL2866787	0.72	CES2 (0.50)	CES2CES1PARP1HDAC1HDAC6
	SCHEMBL16579784	0.72	ALDH1A1 (0.41)	CES2CES1UNGKMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.