Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634410 | 0.92 | ATM (0.44) | TSHRCHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL28633889 | 0.83 | ALOX15 (0.34) | MAPTALOX15CACNA1BAPBA1 | |
| SCHEMBL26101345 | 0.77 | TSHR (0.43) | TSHRCHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL27419567 | 0.75 | HCAR2 (0.54) | TSHRCHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL2547540 | 0.74 | LMNA (0.57) | TSHRCHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL28941942 | 0.72 | TSHR (0.45) | TSHRCHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL21977964 | 0.71 | NFE2L2 (0.55) | CYP2C19MAPTHCAR2ALOX15ALDH1A1 | |
| SCHEMBL4198066 | 0.71 | TSHR (0.67) | TSHRCHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL30525718 | 0.71 | LMNA (0.62) | TSHRCHRNB2CHRNA4CHRM2CHRM4 | |
| SCHEMBL27876632 | 0.70 | ATM (0.50) | TSHRATMMAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108472411-B | High impact toughness transparent prosthetic materials with low residual MMA content | 古莎有限公司 | 2021-10-01 | — | — | CN | disclosed |