Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28926290 | 0.89 | CDK9 (0.43) | CDK9SMN1; SMN2KDM4EGAAASAH1 | |
| SCHEMBL28652315 | 0.85 | CDK9 (0.42) | CDK9SMN1; SMN2KDM4EGAAASAH1 | |
| SCHEMBL28638729 | 0.85 | CDK9 (0.42) | CDK9SMN1; SMN2KDM4EKMT2AGAA | |
| SCHEMBL28646718 | 0.83 | CDK9 (0.41) | CDK9SMN1; SMN2KDM4EKMT2AGAA | |
| SCHEMBL21900263 | 0.83 | CDK9 (0.44) | CDK9KDM4EKMT2AALDH1A1POLB | |
| SCHEMBL28639222 | 0.82 | CDK9 (0.40) | CDK9SMN1; SMN2KDM4EKMT2AGAA | |
| SCHEMBL28660748 | 0.82 | SMN1; SMN2 (0.51) | CDK9SMN1; SMN2KDM4EKMT2AGAA | |
| SCHEMBL28644072 | 0.81 | CDK9 (0.40) | CDK9SMN1; SMN2KDM4EKMT2AGAA | |
| SCHEMBL28652146 | 0.81 | CDK9 (0.40) | CDK9SMN1; SMN2KDM4EKMT2AGAA | |
| SCHEMBL28657237 | 0.80 | CDK9 (0.39) | CDK9SMN1; SMN2KDM4EKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3708566-B1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2023-02-08 | — | — | EP | disclosed |
| CN-107428744-B | Novel heterocyclic compounds and their use in medicine and cosmetics | 盖尔德马研究及发展公司 | 2021-09-24 | — | — | CN | disclosed |