Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 3/20 | 0.33 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28639222 | 0.93 | CDK9 (0.40) | CDK9SMN1; SMN2KDM4EGAATNF | |
| SCHEMBL17870748 | 0.86 | CDK9 (0.39) | CDK9KDM4EMAPT | |
| SCHEMBL28926290 | 0.83 | CDK9 (0.43) | CDK9SMN1; SMN2KDM4EGAATNF | |
| SCHEMBL28638729 | 0.82 | CDK9 (0.42) | CDK9SMN1; SMN2KDM4EGAATNF | |
| SCHEMBL28646718 | 0.81 | CDK9 (0.41) | CDK9SMN1; SMN2KDM4EGAATNF | |
| SCHEMBL19873980 | 0.81 | ALDH1A1 (0.33) | CDK9TNF | |
| SCHEMBL28645790 | 0.80 | CDK9 (0.44) | CDK9SMN1; SMN2KDM4EGAATNF | |
| SCHEMBL28644072 | 0.79 | CDK9 (0.40) | CDK9SMN1; SMN2KDM4EGAAASAH1 | |
| SCHEMBL28652146 | 0.79 | CDK9 (0.40) | CDK9SMN1; SMN2KDM4EGAATNF | |
| SCHEMBL17870749 | 0.78 | CDK9 (0.40) | CDK9KDM4EKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3708566-B1 | NOVEL HETEROCYCLIC COMPOUNDS AND THE USE THEREOF IN MEDICINE AND IN COSMETICS | GALDERMA RES & DEV (FR) | 2023-02-08 | — | — | EP | disclosed |
| CN-107428744-B | Novel heterocyclic compounds and their use in medicine and cosmetics | 盖尔德马研究及发展公司 | 2021-09-24 | — | — | CN | disclosed |