Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28645847 | 1.00 | MAOA (0.53) | MAOAMAOBMAPTALDH1A1NPSR1 | |
| SCHEMBL29624601 | 1.00 | MAOA (0.53) | MAOAMAOBMAPTALDH1A1NPSR1 | |
| SCHEMBL14822865 | 0.90 | MAPT (0.58) | MAPTALDH1A1NPSR1KDM4EPKM | |
| SCHEMBL3811532 | 0.90 | MAPT (0.58) | MAPTALDH1A1NPSR1KDM4EPKM | |
| SCHEMBL3811533 | 0.90 | MAPT (0.58) | MAPTALDH1A1NPSR1KDM4EPKM | |
| SCHEMBL7899300 | 0.80 | POLB (0.55) | MAPTALDH1A1NPSR1KDM4EPKM | |
| SCHEMBL4994672 | 0.80 | POLB (0.55) | MAPTALDH1A1NPSR1KDM4EPKM | |
| SCHEMBL11887911 | 0.80 | CCNB2 (0.62) | MAPTALDH1A1NPSR1KDM4EPKM | |
| SCHEMBL10633969 | 0.79 | ALDH1A1 (0.55) | MAOAMAPTALDH1A1NPSR1KDM4E | |
| SCHEMBL4994853 | 0.79 | ALDH1A1 (0.53) | MAPTALDH1A1NPSR1KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113429422-B | Thienoquinolone compound and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2022-05-10 | — | — | CN | disclosed |
| CN-113429422-A | Thienoquinolone compound and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2021-09-24 | — | — | CN | disclosed |