Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 13/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3687014 | 0.84 | MET (0.48) | METJAK2MAP4K3MAP4K4ALK | |
| SCHEMBL12004389 | 0.84 | MET (0.44) | METJAK2MAP4K3ALK | |
| SCHEMBL28924806 | 0.81 | JAK2 (0.44) | METJAK2MAP4K3ALK | |
| SCHEMBL12004028 | 0.81 | MET (0.68) | METJAK2ALK | |
| SCHEMBL28643808 | 0.81 | MET (0.47) | METJAK2MAP4K3ALK | |
| SCHEMBL28035735 | 0.79 | JAK2 (0.47) | METJAK2MAP4K3ALK | |
| SCHEMBL28642048 | 0.77 | MET (0.46) | METJAK2MAP4K3ALK | |
| SCHEMBL28036128 | 0.77 | JAK2 (0.47) | METJAK2MAP4K3ALK | |
| SCHEMBL28628304 | 0.76 | MET (0.45) | METJAK2MAP4K3ALK | |
| SCHEMBL28515206 | 0.76 | JAK2 (0.62) | METJAK2MAP4K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106659765-B | Use of dianhydrogalactitol and analogs or derivatives thereof for treating non-small cell lung cancer and ovarian cancer | 德玛医药 | 2021-08-13 | — | — | CN | disclosed |