SCHEMBL286464

SCHEMBL286464

O=C1NC(c2ccc(Cl)c(Cl)c2)=C2C(=O)NC(c3ccc(Cl)c(Cl)c3)=C12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 0.50
MEN1 O00255 2/20 0.47
HTT P42858 2/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.47
USP2 O75604 1/20 0.47
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47
PKM P14618 1/20 0.47
ALOX12 P18054 1/20 0.47
CYP1B1 Q16678 1/20 0.43
NOTUM Q6P988 2/20 0.42
ALKBH3 Q96Q83 1/20 0.40
SIRT2 Q8IXJ6 1/20 0.39
PGR P06401 1/20 0.39
GSK3A P49840 3/20 0.38
GSK3B P49841 3/20 0.38
IGF1R P08069 2/20 0.38
INSR P06213 1/20 0.38
PDE3B Q13370 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7750652 0.93 AHR (0.43) AHRMEN1HTTKMT2AKDM4E
SCHEMBL7754317 0.91 AHR (0.42) AHRMEN1HTTKMT2AKDM4E
SCHEMBL12577702 0.90 AHR (0.41) AHRMEN1HTTKMT2AKDM4E
SCHEMBL12424888 0.85 TDP2 (0.51) PGRIGF1RTDP2
SCHEMBL23519815 0.83 PDE3B (0.43) MAPTALKBH3GSK3AGSK3BPDE3B
SCHEMBL12424885 0.83 GSK3A (0.42) MEN1KMT2AKDM4EGAAMAPT
SCHEMBL22625772 0.79 NOTUM (0.35) MEN1HTTKMT2AKDM4EUSP2
SCHEMBL22625732 0.79 GSK3B (0.32) MEN1HTTKMT2AKDM4EUSP2
SCHEMBL12424883 0.79 PTGS2 (0.42) KMT2AGAAPGRGSK3AGSK3B
SCHEMBL12509875 0.79 GSK3A (0.40) MEN1KMT2AKDM4EGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6645257-B1 Obtaining better penetration by treating with soluble pigment precursors under alkaline slightly conditions, acidifying with weak organic acid and thermally regenerating CIBA SPECIALTY CHEMICALS CORPORATION 2003-11-11 US claimed
EP-1218154-B1 PROCESS FOR PIGMENTING WOOD CIBA SC HOLDING AG (CH) 2003-04-09 EP claimed
EP-1218154-A1 PROCESS FOR PIGMENTING WOOD Ciba SC Holding AG (CH) 2002-07-03 EP claimed
WO-2001024983-A1 PROCESS FOR PIGMENTING WOOD CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-04-12 WO claimed
US-5869625-A PAINTS CIBA SPECIALTY CHEMICAL CORPORATION (US) 1999-02-09 US claimed
EP-2658928-B1 SURFACE-MODIFIED PIGMENT PREPARATIONS BASF SE (DE) 2019-03-27 EP disclosed
EP-2038704-B9 COLOR FILTER COMPOSITION BASF SE (DE) 2019-03-27 EP disclosed
EP-2198340-B1 ENCAPSULATED DISPERSIONS COMPRISING ELECTROPHORETICALLY MOBILE ORGANIC COLORANTS BASF SE (DE) 2019-03-13 EP disclosed
EP-2038704-B1 COLOR FILTER COMPOSITION BASF SE (DE) 2018-11-07 EP disclosed
EP-2038701-B1 ENCAPSULATED DISPERSIONS COMPRISING ELECTROPHORETICALLY MOBILE ORGANIC COLORANTS BASF SE (DE) 2017-04-12 EP disclosed
US-9403987-B2 Charged particles BASF SE (DE) 2016-08-02 US disclosed
US-9346963-B2 Surface-modified pigment preparations BASF SE (DE) 2016-05-24 US disclosed
WO-2000033795-A1 COSMETIC PREPARATIONS CONTAINING ORGANIC PIGMENTS FROM THE CLASS OF PYRROLO-[3,4-C]-PYRROLES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-06-15 WO disclosed
WO-2000027930-A1 PROCESS FOR PIGMENTING POROUS METAL OXIDES AND MATERIALS PIGMENTED THEREWITH CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-05-18 WO disclosed
US-6036766-A SPINNING SOLUTIONS, PAINTS, COATINGS, PRINTING INKS CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-03-14 US disclosed
EP-0704497-B1 Mixed crystals and solid solutions of 1,4 diketopyrrolopyrroles CIBA SC HOLDING AG (CH) 1999-12-15 EP disclosed
EP-0811625-A2 Process for preparing diketopyrrolopyrrole derivatives Ciba SC Holding AG (CH) 1997-12-10 EP disclosed
EP-0790281-A2 Pigment compositions Ciba Spezialitätenchemie Holding AG (Ciba Spécialités Chimiques Holding SA) (Ciba Specialty Chemicals Holding Inc.) (CH) 1997-08-20 EP disclosed
EP-0719842-A2 Pigment compositions for coatings CIBA-GEIGY AG (CH) 1996-07-03 EP disclosed
EP-0704497-A1 Mixed crystals and solid solutions of 1,4 diketopyrrolopyrroles CIBA-GEIGY AG (CH) 1996-04-03 EP disclosed