Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.43 |
| ▸ | GSK3B | P49841 | 8/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL286464 | 0.93 | AHR (0.50) | AHRGSK3BGSK3AMEN1HTT | |
| SCHEMBL7754317 | 0.88 | AHR (0.42) | AHRGSK3BMEN1HTTKMT2A | |
| SCHEMBL91966 | 0.87 | PTGS2 (0.50) | GSK3BGSK3AKDM4EGAAMAPT | |
| SCHEMBL12577702 | 0.87 | AHR (0.41) | AHRGSK3BGSK3AMEN1HTT | |
| SCHEMBL12424888 | 0.82 | TDP2 (0.51) | PTGS2TDP2 | |
| SCHEMBL3823878 | 0.82 | PTGS2 (0.56) | AHRGSK3BGSK3AMEN1HTT | |
| SCHEMBL13204641 | 0.81 | GSK3B (0.52) | GSK3BGSK3ATDP2 | |
| SCHEMBL1557806 | 0.80 | GSK3B (0.54) | GSK3BMEN1KMT2AKDM4EGAA | |
| SCHEMBL7753950 | 0.79 | CYP2D6 (0.46) | GSK3BGSK3AMEN1KMT2AMAPT | |
| SCHEMBL21419776 | 0.79 | GSK3B (0.58) | GSK3BGSK3AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765919-B1 | Monophasic solid solutions with asymmetrical pyrrolo-(4-3-c)-pyrroles as host | CIBA SC HOLDING AG (CH) | 2001-02-21 | — | — | EP | disclosed |
| US-5756746-A | KETOPYRROLES AND QUINACRIDONES FOR LIGHT STABLE AND WEATHER RESISTANT COLOR COMPOSITIONS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0765919-A2 | Monophasic solid solutions with asymmetrical pyrrolo-(4-3-c)-pyrroles as host | Ciba SC Holding AG (CH) | 1997-04-02 | — | — | EP | disclosed |