Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL724142 | 1.00 | CA5A (0.50) | CA5ACA5BTSHRALDH1A1ATM | |
| Nitric Acid SCHEMBL15263924 | 1.00 | CA5A (0.50) | CA5ACA5BTSHRALDH1A1ATM | |
| Nitric Acid SCHEMBL28278313 | 0.94 | CA5A (0.44) | CA5ACA5BTSHRALDH1A1ATM | |
| SCHEMBL28418723 | 0.84 | TSHR (0.44) | TSHRALDH1A1ATML3MBTL1CYP1A2 | |
| Silver SCHEMBL7481689 | 0.84 | TSHR (0.44) | TSHRALDH1A1ATML3MBTL1CYP1A2 | |
| Nitric Acid SCHEMBL7914057 | 0.81 | — | — | |
| N,N-Dimethylethanaminium SCHEMBL11168010 | 0.81 | — | — | |
| Nitroethane SCHEMBL8669596 | 0.81 | TSHR (0.69) | TSHRALDH1A1ATML3MBTL1CYP1A2 | |
| Nitric Acid SCHEMBL2217867 | 0.79 | CA5A (0.67) | CA5ACA5BTSHRALDH1A1TDP1 | |
| Nitric Acid SCHEMBL2217977 | 0.79 | CA5A (0.67) | CA5ACA5BTSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113620883-B | Preparation method of semi-proton type compound, product and application thereof | 西南大学 | 2023-04-11 | — | — | CN | disclosed |
| CN-113620883-A | Preparation method of semi-proton type compound, product and application thereof | 西南大学 | 2021-11-09 | — | — | CN | disclosed |