Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 4/20 | 0.40 |
| ▸ | IDH1 | O75874 | 8/20 | 0.39 |
| ▸ | IDH2 | P48735 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16321221 | 0.80 | ALDH1A1 (0.44) | TGFBR1IDH1IDH2CSNK1DCSNK1E | |
| SCHEMBL19207002 | 0.77 | HCRTR1 (0.47) | TGFBR1IDH1IDH2CSNK1DCSNK1E | |
| SCHEMBL28658603 | 0.73 | BRD4 (0.48) | TGFBR1 | |
| SCHEMBL19806307 | 0.70 | NOTUM (0.42) | TGFBR1IDH1IDH2CSNK1DCSNK1E | |
| SCHEMBL19806523 | 0.70 | GABRA1 (0.47) | TGFBR1IDH1IDH2NOTUMGABRA1 | |
| SCHEMBL20028677 | 0.69 | TGFBR1 (0.47) | TGFBR1CSNK1DCSNK1ENOTUMGRIN2B | |
| SCHEMBL16399255 | 0.69 | HTR2B (0.48) | IDH1IDH2NOTUMGABRA1GABRG2 | |
| SCHEMBL31003055 | 0.68 | NOTUM (0.38) | TGFBR1IDH1IDH2NOTUMGABRA1 | |
| SCHEMBL29320448 | 0.68 | NOTUM (0.38) | TGFBR1IDH1IDH2NOTUMGABRA1 | |
| SCHEMBL16116264 | 0.68 | KMT2A (0.40) | CSNK1DCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109219606-B | Halogen substituted piperidines as orexin receptor modulators | 阿斯利康(瑞典)有限公司 | 2021-10-01 | — | — | CN | disclosed |