Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.50 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8735699 | 0.83 | TGFBR1 (0.43) | TGFBR1TDP1 | |
| SCHEMBL4563862 | 0.78 | TGFBR1 (0.42) | TGFBR1 | |
| SCHEMBL6240724 | 0.76 | TGFBR1 (0.41) | TGFBR1GRIK1GRIK2 | |
| SCHEMBL29020061 | 0.76 | TGFBR1 (0.41) | TGFBR1 | |
| SCHEMBL340694 | 0.76 | TGFBR1 (0.47) | TGFBR1TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4442289 | 0.75 | TGFBR1 (0.46) | TGFBR1TDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28412043 | 0.75 | TGFBR1 (0.46) | TGFBR1TDP1ALDH1A1 | |
| SCHEMBL18139413 | 0.73 | TGFBR1 (0.57) | TGFBR1TDP1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL411710 | 0.73 | TGFBR1 (0.44) | TGFBR1TDP1 | |
| Hydrochloric Acid SCHEMBL28634771 | 0.72 | TGFBR1 (0.43) | TGFBR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113613677-A | Polymeric drug delivery conjugates and methods of making and using the same | 犹他大学研究基金会 | 2021-11-05 | — | — | CN | claimed |
| CN-113613677-A | Polymeric drug delivery conjugates and methods of making and using the same | 犹他大学研究基金会 | 2021-11-05 | — | — | CN | disclosed |