Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 4/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.36 |
| ▸ | DNPEP | Q9ULA0 | 3/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28648657 | 0.83 | TGFBR1 (0.50) | TGFBR1TDP1 | |
| SCHEMBL4563862 | 0.79 | TGFBR1 (0.42) | TGFBR1SLC1A3SLC1A2SLC1A1CA1 | |
| SCHEMBL6240724 | 0.78 | TGFBR1 (0.41) | TGFBR1SLC1A2SLC1A1TSHR | |
| SCHEMBL29020061 | 0.78 | TGFBR1 (0.41) | TGFBR1ANPEP | |
| SCHEMBL340694 | 0.78 | TGFBR1 (0.47) | TGFBR1RXFP1TDP1 | |
| Hydrochloric Acid SCHEMBL28412043 | 0.76 | TGFBR1 (0.46) | TGFBR1RXFP1TDP1 | |
| Hydrochloric Acid SCHEMBL4442289 | 0.76 | TGFBR1 (0.46) | TGFBR1RXFP1TDP1 | |
| SCHEMBL717760 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL411710 | 0.74 | TGFBR1 (0.44) | TGFBR1RXFP1TDP1 | |
| SCHEMBL472236 | 0.73 | TGFBR1 (0.43) | TGFBR1TSHRRXFP1CA1TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647143-B1 | AZLACTONE-FUNCTIONAL SUBSTRATES, CORNEAL PROSTHESES, AND MANUFACTURE AND USE THEREOF | MINNESOTA MINING & MFG (US) | 1998-01-28 | — | — | EP | claimed |
| EP-0647143-A1 | AZLACTONE-FUNCTIONAL SUBSTRATES, CORNEAL PROSTHESES, AND MANUFACTURE AND USE THEREOF | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-04-12 | — | — | EP | claimed |
| US-5292514-A | Hydrogel coupled to biologically active material through azalactone moiety | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-03-08 | — | — | US | claimed |
| WO-1994000165-A2 | AZLACTONE-FUNCTIONAL SUBSTRATES, CORNEAL PROSTHESES, AND MANUFACTURE AND USE THEREOF | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-01-06 | — | — | WO | claimed |