Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.62 |
| ▸ | MMP9 | P14780 | 5/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | ACE | P12821 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | APAF1 | O14727 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MPO | P05164 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078918 | 0.86 | KMT2A (0.58) | MMP2MMP9ALOX15ACEKMT2A | |
| SCHEMBL231803 | 0.86 | ALOX15 (0.66) | MMP2MMP9ALOX15ACEKMT2A | |
| SCHEMBL231804 | 0.86 | ALOX15 (0.66) | MMP2MMP9ALOX15ACEKMT2A | |
| SCHEMBL30782236 | 0.84 | ALOX15 (0.70) | MMP2MMP9ALOX15ACEKMT2A | |
| SCHEMBL27851269 | 0.84 | ALOX15 (0.63) | MMP2MMP9ALOX15ACEKMT2A | |
| SCHEMBL31210300 | 0.84 | ALOX15 (0.67) | MMP2MMP9ALOX15ACEKMT2A | |
| SCHEMBL29063383 | 0.84 | ALOX15 (0.63) | MMP2MMP9ALOX15ACEKMT2A | |
| SCHEMBL28200409 | 0.84 | ALOX15 (0.63) | MMP2MMP9ALOX15ACEKMT2A | |
| SCHEMBL7558085 | 0.84 | ALOX15 (0.67) | MMP2MMP9ALOX15ACEKMT2A | |
| SCHEMBL7558077 | 0.84 | ALOX15 (0.67) | MMP2MMP9ALOX15ACEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113646048-A | Anti-cancer combination therapy | 勃林格殷格翰国际有限公司 | 2021-11-12 | — | — | CN | disclosed |