SCHEMBL28200409

SCHEMBL28200409

O=CONC(Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.63
ACE P12821 3/20 0.59
SMN1; SMN2 Q16637 1/20 0.58
ITGB2 P05107 3/20 0.57
ICAM1 P05362 3/20 0.57
ITGAL P20701 3/20 0.57
MMP2 P08253 2/20 0.57
MMP9 P14780 2/20 0.57
KDM4E B2RXH2 2/20 0.56
MAPT P10636 2/20 0.56
KMT2A Q03164 2/20 0.56
APAF1 O14727 1/20 0.56
POLB P06746 1/20 0.56
RECQL P46063 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
MEN1 O00255 1/20 0.56
LMNA P02545 1/20 0.56
MPO P05164 1/20 0.56
TSHR P16473 1/20 0.56
BLM P54132 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27851269 1.00 ALOX15 (0.63) ALOX15ACESMN1; SMN2ITGB2ICAM1
SCHEMBL29063383 1.00 ALOX15 (0.63) ALOX15ACESMN1; SMN2ITGB2ICAM1
SCHEMBL7558077 0.85 ALOX15 (0.67) ALOX15ACESMN1; SMN2ITGB2ICAM1
SCHEMBL7558085 0.85 ALOX15 (0.67) ALOX15ACESMN1; SMN2ITGB2ICAM1
SCHEMBL231803 0.85 ALOX15 (0.66) ALOX15ACESMN1; SMN2ITGB2ICAM1
SCHEMBL231804 0.85 ALOX15 (0.66) ALOX15ACESMN1; SMN2ITGB2ICAM1
SCHEMBL28648798 0.84 MMP2 (0.62) ALOX15ACESMN1; SMN2ITGB2ICAM1
SCHEMBL120495 0.83 ALOX15 (0.67) ALOX15ACESMN1; SMN2ITGB2ICAM1
SCHEMBL120493 0.83 ALOX15 (0.67) ALOX15ACESMN1; SMN2ITGB2ICAM1
SCHEMBL5519036 0.83 ALOX15 (0.67) ALOX15ACESMN1; SMN2ITGB2ICAM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116512707-A Nanofiber fabric and preparation method thereof 上海诺宝尔纺织科技有限公司 2023-08-01 CN disclosed
CN-107743481-A Indoleamine 2, 3-dioxygenase inhibitors for the treatment of cancer 百时美施贵宝公司 2018-02-27 CN disclosed
CN-107743490-A For the indoleamine 2 for the treatment of cancer, 3 dioxygenase inhibitors 百时美施贵宝公司 2018-02-27 CN disclosed