Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 18/20 | 0.53 |
| ▸ | CRBN | Q96SW2 | 18/20 | 0.53 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29347124 | 0.95 | DDB1 (0.47) | DDB1CRBNCACNA1GCACNA1HKDM4E | |
| SCHEMBL29347429 | 0.94 | DDB1 (0.48) | DDB1CRBNCACNA1GCACNA1HKDM4E | |
| SCHEMBL24269179 | 0.85 | DDB1 (0.48) | DDB1CRBN | |
| SCHEMBL22512101 | 0.85 | DDB1 (0.58) | DDB1CRBNCACNA1GCACNA1HALDH1A1 | |
| SCHEMBL22511713 | 0.85 | DDB1 (0.58) | DDB1CRBNCACNA1GCACNA1HALDH1A1 | |
| SCHEMBL31586555 | 0.85 | DDB1 (0.58) | DDB1CRBNCACNA1GCACNA1HALDH1A1 | |
| SCHEMBL31068578 | 0.85 | HTR4 (0.39) | DDB1CRBNCACNA1GCACNA1HKDM4E | |
| SCHEMBL25122889 | 0.84 | DDB1 (0.45) | DDB1CRBNKDM4EALDH1A1 | |
| SCHEMBL31068531 | 0.84 | DDB1 (0.45) | DDB1CRBNKDM4EALDH1A1 | |
| SCHEMBL29347122 | 0.83 | HTR4 (0.40) | CACNA1GCACNA1HKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113710661-B | Compounds and methods for treating cancer | 上海睿跃生物科技有限公司 | 2022-11-22 | — | — | CN | disclosed |
| CN-113710661-A | Compounds and methods for treating cancer | 上海睿跃生物科技有限公司 | 2021-11-26 | — | — | CN | disclosed |
| CN-113646002-A | Cyclic AMP response element binding protein (CBP) and/or 300KDA adenovirus E1A binding protein (P300) degradation compounds and methods of use | 上海睿跃生物科技有限公司 | 2021-11-12 | — | — | CN | disclosed |