Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 2/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31068578 | 0.85 | HTR4 (0.39) | HTR4CACNA1GCACNA1HOPRL1OPRM1 | |
| SCHEMBL29347124 | 0.84 | DDB1 (0.47) | HTR4CACNA1GCACNA1HOPRL1OPRM1 | |
| SCHEMBL28649449 | 0.83 | DDB1 (0.53) | CACNA1GCACNA1HKDM4EALDH1A1 | |
| SCHEMBL29347429 | 0.83 | DDB1 (0.48) | HTR4CACNA1GCACNA1HOPRL1OPRM1 | |
| SCHEMBL29347132 | 0.74 | DDB1 (0.37) | HTR4CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL31068531 | 0.73 | DDB1 (0.45) | KDM4EALDH1A1CNR2 | |
| SCHEMBL31730014 | 0.71 | DDB1 (0.50) | CNR2 | |
| SCHEMBL29347058 | 0.71 | ALDH1A1 (0.44) | OPRL1OPRM1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL31068515 | 0.70 | DDB1 (0.51) | OPRL1OPRM1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL24269179 | 0.69 | DDB1 (0.48) | HTR4OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024150815-A1 | CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR | 田辺三菱製薬株式会社 | 2024-07-18 | — | — | WO | disclosed |