Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | NQO1 | P15559 | 2/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | ANTXR2 | P58335 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6415919 | 0.71 | CYP3A4 (0.50) | KDM4EMEN1MAPTKMT2APTGS1 | |
| SCHEMBL8745776 | 0.67 | NQO1 (0.59) | KDM4EMEN1MAPTKMT2ANQO1 | |
| SCHEMBL12704738 | 0.67 | MCL1 (0.40) | KDM4EMEN1KMT2ACYP3A4 | |
| SCHEMBL1047858 | 0.66 | ALDH1A1 (0.46) | USP2CYP3A4 | |
| SCHEMBL31207104 | 0.66 | CYP3A4 (0.56) | MEN1MAPTKMT2APTGS1PTGS2 | |
| SCHEMBL29092099 | 0.66 | MCL1 (0.39) | KDM4EMEN1MAPTKMT2AGAA | |
| SCHEMBL1225856 | 0.66 | ACHE (0.46) | KDM4EMAPT | |
| SCHEMBL11860188 | 0.66 | KDM4E (0.40) | KDM4EMEN1MAPTKMT2APTGS1 | |
| SCHEMBL11131991 | 0.65 | — | — | |
| SCHEMBL21776517 | 0.65 | MCL1 (0.38) | KDM4EMEN1KMT2ACYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108913731-B | Pyran compound with immunosuppressive activity and preparation method and application thereof | 海南大学 | 2021-11-16 | — | — | CN | disclosed |
| CN-108913731-A | A kind of pyran compounds and its preparation method and application with immunosuppressive activity | 海南大学 | 2018-11-30 | — | — | CN | disclosed |