Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | TYK2 | P29597 | 2/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | GNRHR | P30968 | 1/20 | 0.33 |
| ▸ | HPD | P32754 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30225594 | 0.96 | NMT1 (0.39) | NMT1DDB1CRBNDRD2SLC6A4 | |
| SCHEMBL28644888 | 0.96 | NMT1 (0.40) | NMT1DDB1CRBNPIK3CAPRKDC | |
| SCHEMBL31282297 | 0.85 | NMT1 (0.39) | NMT1DDB1CRBNDRD2SLC6A4 | |
| SCHEMBL29991433 | 0.84 | DDB1 (0.39) | DDB1CRBNDRD2SLC6A4PIK3CA | |
| SCHEMBL26634973 | 0.83 | DDB1 (0.39) | DDB1CRBNDRD2SLC6A4PIK3CA | |
| SCHEMBL30225615 | 0.83 | KHK (0.40) | DDB1CRBNDRD2SLC6A4PIK3CA | |
| SCHEMBL30225575 | 0.82 | HDAC1 (0.40) | DDB1CRBNDRD2SLC6A4HDAC1 | |
| SCHEMBL29172794 | 0.82 | DDB1 (0.38) | DDB1CRBNDRD2SLC6A4PIK3CA | |
| SCHEMBL31282399 | 0.82 | DDB1 (0.38) | DDB1CRBNDRD2SLC6A4PIK3CA | |
| SCHEMBL26635076 | 0.82 | DDB1 (0.38) | DDB1CRBNDRD2SLC6A4PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423427-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2021-09-21 | — | — | CN | disclosed |