Nitrogen

Nitrogen

SCHEMBL28650271

N#N.Nc1cc(Br)ccc1C(=O)O

nearest known ligand 0.66

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.66
GLA P06280 1/20 0.66
ALDH1A1 P00352 4/20 0.50
HPGD P15428 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MAPT P10636 6/20 0.49
TDP1 Q9NUW8 3/20 0.49
CYP3A4 P08684 2/20 0.49
POLB P06746 2/20 0.49
ALOX15 P16050 1/20 0.49
PPM1B O75688 1/20 0.47
IDO1 P14902 1/20 0.46
DGAT1 O75907 1/20 0.44
KMT2A Q03164 4/20 0.44
RXFP1 Q9HBX9 2/20 0.44
GFER P55789 1/20 0.44
PLAU P00749 1/20 0.43
MEN1 O00255 3/20 0.42
THRB P10828 2/20 0.42
USP2 O75604 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL148392 0.96 KDM4E (0.70) KDM4EGLAALDH1A1HPGDHSD17B10
Hydrochloric Acid SCHEMBL6359504 0.94 KDM4E (0.68) KDM4EGLAALDH1A1HPGDHSD17B10
SCHEMBL15824364 0.81 KDM4E (0.53) KDM4EGLAALDH1A1HPGDHSD17B10
SCHEMBL159651 0.79 DGAT1 (0.62) KDM4EGLAALDH1A1HPGDMAPT
SCHEMBL29622752 0.79 KDM4E (1.00) KDM4EGLAALDH1A1HPGDMAPT
SCHEMBL145485 0.79 KDM4E (1.00) KDM4EGLAALDH1A1HPGDMAPT
SCHEMBL3895566 0.78 KDM4E (0.49) KDM4EGLAALDH1A1HPGDHSD17B10
SCHEMBL1189192 0.78 KDM4E (0.52) KDM4EGLAALDH1A1HPGDHSD17B10
SCHEMBL13967325 0.78 KDM4E (0.52) KDM4EGLAALDH1A1HPGDMAPT
SCHEMBL16230413 0.77 KDM4E (0.52) KDM4EGLAALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113651760-B Pyrimidine selenobenzoic acid derivative, preparation method thereof and application of pyrimidine selenobenzoic acid derivative as herbicide 常州大学 2023-07-25 CN disclosed
CN-113651760-A Pyrimidine selenium benzoic acid derivative, preparation method thereof and application of pyrimidine selenium benzoic acid derivative as herbicide 常州大学 2021-11-16 CN disclosed