Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | GLA | P06280 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | PPM1B | O75688 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6359504 | 0.98 | KDM4E (0.68) | KDM4EGLAALDH1A1HPGDHSD17B10 | |
| Nitrogen SCHEMBL28650271 | 0.96 | KDM4E (0.66) | KDM4EGLAALDH1A1HPGDHSD17B10 | |
| SCHEMBL15824364 | 0.85 | KDM4E (0.53) | KDM4EGLAALDH1A1HPGDHSD17B10 | |
| SCHEMBL29622752 | 0.83 | KDM4E (1.00) | KDM4EGLAALDH1A1HPGDMAPT | |
| SCHEMBL145485 | 0.83 | KDM4E (1.00) | KDM4EGLAALDH1A1HPGDMAPT | |
| SCHEMBL159651 | 0.83 | DGAT1 (0.62) | KDM4EGLAALDH1A1HPGDMAPT | |
| SCHEMBL3895566 | 0.81 | KDM4E (0.49) | KDM4EGLAALDH1A1HPGDHSD17B10 | |
| SCHEMBL1189192 | 0.81 | KDM4E (0.52) | KDM4EGLAALDH1A1HPGDHSD17B10 | |
| SCHEMBL13967325 | 0.81 | KDM4E (0.52) | KDM4EGLAALDH1A1HPGDMAPT | |
| SCHEMBL16230413 | 0.80 | KDM4E (0.52) | KDM4EGLAALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 960 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084784-A | Preparation method of 5-bromoquinoline-8-carbonitrile | 武汉桀升生物科技有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-117466759-A | Preparation method of 2-amino-4-bromo-5-chlorobenzoic acid | 阜新清稷升科技有限公司 | 2024-01-30 | — | — | CN | claimed |
| CN-113461661-B | 6- (pyridin-3-yl) quinazoline-4 (3H) -ketone derivative and preparation and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2023-11-28 | — | — | CN | claimed |
| CN-115010671-B | One-step synthesis method of 2-substituted quinazolinone | 江苏大学 | 2023-10-10 | — | — | CN | claimed |
| CN-111499513-B | Synthesis method of 2,3,4, 5-tetrabromobenzoate | 上海毕得医药科技股份有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-115010671-A | One-step synthesis method of 2-substituted quinazolinone | 江苏大学 | 2022-09-06 | — | — | CN | claimed |
| CN-110433667-B | Anti-pollution anti-scaling separation membrane and preparation method thereof | 天津大学 | 2022-03-22 | — | — | CN | claimed |
| CN-114057917-A | Post-treatment ashless dispersant and preparation method thereof | 中国石油天然气股份有限公司 | 2022-02-18 | — | — | CN | claimed |
| CN-113461661-A | 6- (pyridine-3-yl) quinazoline-4 (3H) -ketone derivative and preparation and application thereof | 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) | 2021-10-01 | — | — | CN | claimed |
| CN-107072201-B | Biofilm formation inhibitor and/or remover, and biofilm formation inhibiting method and/or removing method | 星光PMC株式会社 | 2020-11-13 | — | — | CN | claimed |
| CN-103554007-B | Novel 4, 5-substituted-7-methyl formate indole diketone derivative and application thereof in antitumor drugs | TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-05-18 | — | — | CN | claimed |
| CN-105503744-A | Diphenyl urea compound containing quinazolinone and preparation method and application of diphenyl urea compound | UNIV XIAN JIAOTONG | 2016-04-20 | — | — | CN | claimed |
| US-20150320042-A1 | BIOACTIVE ANILINE COPOLYMERS | AUCKLAND UNISERVICES LIMITED (NZ) | 2015-11-12 | — | — | US | claimed |
| CN-102898369-A | 3-amino-7-bromoquinoline-2-ethyl formate and preparation method thereof | SHANGHAI SHUYA MEDICAL TECHNOLOGY CO LTD | 2013-01-30 | — | — | CN | claimed |
| CN-101808514-A | bioactive aniline copolymers | AUCKLAND UNISERVICES LTD | 2010-08-18 | — | — | CN | claimed |
| US-20100196306-A1 | BIOACTIVE ANILINE COPOLYMERS | AUCKLAND UNISERVICES LIMITED (NZ) | 2010-08-05 | — | — | US | claimed |
| CN-101768265-A | Modified nylon and preparation method thereof | UNIV SUZHOU | 2010-07-07 | — | — | CN | claimed |
| EP-2190285-A1 | BIOACTIVE ANILINE COPOLYMERS | AUCKLAND UNISERVICES LIMITED (NZ) | 2010-06-02 | — | — | EP | claimed |
| WO-2009041837-A1 | BIOACTIVE ANILINE COPOLYMERS | AUCKLAND UNISERVICES LIMITED (NZ) | 2009-04-02 | — | — | WO | claimed |
| US-5744638-A | Process for the preparation of haloanthranilic acids | RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) | 1998-04-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150320042-A1 | BIOACTIVE ANILINE COPOLYMERS | ALKBH1, L3MBTL3, AGXT | KDM4E 313/4885GLA 1563/4885ALDH1A1 3862/4885 |
| US-20100196306-A1 | BIOACTIVE ANILINE COPOLYMERS | H1-3, L3MBTL3, ALKBH1 | KDM4E 306/4885GLA 1595/4885ALDH1A1 3627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.