Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.40 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28953843 | 0.98 | TSHR (0.41) | TSHRBBOX1HPGDALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL27662712 | 0.84 | TSHR (0.41) | TSHRMAPTHPGDGALR3BLM | |
| SCHEMBL3764876 | 0.81 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL28801583 | 0.81 | TSHR (0.37) | TSHRHPGD | |
| Hydrochloric Acid SCHEMBL28418892 | 0.81 | TSHR (0.39) | TSHRMAPTHPGDGALR3BLM | |
| Hydrochloric Acid SCHEMBL27618636 | 0.81 | TSHR (0.39) | TSHRBBOX1MAPTHPGDGALR3 | |
| Hydrochloric Acid SCHEMBL6023880 | 0.81 | TSHR (0.39) | TSHRMAPTHPGDGALR3BLM | |
| Iodide SCHEMBL27893214 | 0.80 | TSHR (0.41) | TSHRHPGDALDH1A1TP53HIF1A | |
| Fluoride Ion SCHEMBL28241928 | 0.80 | TSHR (0.41) | TSHRHPGDALDH1A1TP53HIF1A | |
| Bromide SCHEMBL28241929 | 0.80 | TSHR (0.41) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110938416-B | Profile control agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2021-11-19 | — | — | CN | claimed |
| CN-110938416-A | Profile control agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2020-03-31 | — | — | CN | claimed |
| CN-110938416-B | Profile control agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2021-11-19 | — | — | CN | disclosed |
| CN-110938416-A | Profile control agent and preparation method and application thereof | 中国石油化工股份有限公司 | 2020-03-31 | — | — | CN | disclosed |