SCHEMBL2867415

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2871320	0.95	PDPK1 (0.66)	ULK1ITKPDPK1MAPK10GSK3B
	SCHEMBL2861621	0.88	PDPK1 (0.59)	ULK1ITKPDPK1MAPK10GSK3B
	SCHEMBL2861016	0.81	ITK (0.68)	ITKMAPKAPK2
	SCHEMBL2865036	0.81	PDPK1 (0.65)	ULK1ITKPDPK1
	Hydrochloric Acid SCHEMBL27396112	0.79	CYP1A2 (0.57)	ULK1HTR1AHTR1DHTR2BHTR6
	SCHEMBL8251891	0.78	ULK1 (0.61)	ULK1ITKPDPK1GSK3BCLK2
	SCHEMBL13854959	0.78	ULK1 (0.62)	ULK1ITKPDPK1GSK3BCLK2
	SCHEMBL8254064	0.78	ULK1 (0.59)	ULK1ITKPDPK1
	SCHEMBL14074986	0.78	GSK3B (0.56)	PDPK1MAPK10GSK3B
	SCHEMBL4338506	0.77	GSK3B (0.50)	ITKPDPK1GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.