SCHEMBL2865039

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2867399	0.89	EGFR (0.50)	GSK3ACCNB2CDK1CCNB1CCNB3
	SCHEMBL2860793	0.83	GSK3A (0.41)	GSK3ACCNB2CDK1CCNB1CCNB3
	SCHEMBL4335929	0.78	DYRK1A (0.46)	MAPK1MAP2K4CLK2CLK3DYRK1A
	SCHEMBL4343203	0.78	WNT1 (0.52)	MAPK1MAP2K4DYRK1ACSNK1DWNT1
	SCHEMBL4333014	0.77	GSK3B (0.65)	GSK3AGSK3BMAP2K4CLK2WNT1
	SCHEMBL2863515	0.77	NTRK1 (0.49)	GSK3AGSK3BMAPK1MAP2K4CLK2
	SCHEMBL4332627	0.73	MAPK8 (0.49)	MAPK1MAP2K4DYRK1ACSNK1DWNT1
	SCHEMBL13198260	0.73	NTRK1 (0.49)	GSK3AGSK3BMAPK1MAP2K4EGFR
	SCHEMBL2867504	0.73	CDK4 (0.45)	GSK3AGSK3BMAPK1MAPK14
	SCHEMBL27558524	0.72	MAP2K4 (0.54)	GSK3AGSK3BMAPK1MAP2K4DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.