Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 8/20 | 0.38 |
| ▸ | HTR2C | P28335 | 7/20 | 0.38 |
| ▸ | HTR2A | P28223 | 6/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30493286 | 0.86 | STAT3 (0.44) | STAT3PARP1HTR2BHTR2CHTR2A | |
| SCHEMBL30069969 | 0.83 | PARP1 (0.43) | STAT3PARP1HTR2BHTR2CHTR2A | |
| SCHEMBL21998222 | 0.80 | STAT3 (0.58) | STAT3MAP1LC3B | |
| SCHEMBL29414342 | 0.79 | HTR2B (0.41) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL28692317 | 0.79 | HTR2B (0.41) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL31129783 | 0.72 | HTR2B (0.43) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL19481469 | 0.72 | STAT3 (0.46) | STAT3MAP1LC3BMAPK1 | |
| SCHEMBL660471 | 0.71 | HTR2B (0.62) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30659847 | 0.71 | PARP1 (0.49) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30698072 | 0.71 | HTR2B (0.62) | PARP1HTR2BHTR2CHTR2AHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423427-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2021-09-21 | — | — | CN | disclosed |