Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 4/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | MAP1LC3B | Q9GZQ8 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 7/20 | 0.38 |
| ▸ | HTR2C | P28335 | 6/20 | 0.38 |
| ▸ | HTR2A | P28223 | 5/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28650618 | 0.86 | STAT3 (0.39) | STAT3PARP1MAP1LC3BHTR2BHTR2C | |
| SCHEMBL30069969 | 0.84 | PARP1 (0.43) | STAT3PARP1MAP1LC3BHTR2BHTR2C | |
| SCHEMBL28692317 | 0.80 | HTR2B (0.41) | PARP1MAP1LC3BHTR2BHTR2CHTR2A | |
| SCHEMBL29414342 | 0.80 | HTR2B (0.41) | PARP1MAP1LC3BHTR2BHTR2CHTR2A | |
| SCHEMBL19305499 | 0.78 | PARP1 (0.37) | STAT3PARP1HTR2BHTR2CHTR2A | |
| SCHEMBL25226137 | 0.78 | STAT3 (0.67) | STAT3MAP1LC3B | |
| SCHEMBL30462421 | 0.78 | STAT3 (0.67) | STAT3MAP1LC3B | |
| SCHEMBL30493238 | 0.78 | STAT3 (0.67) | STAT3MAP1LC3B | |
| SCHEMBL25431129 | 0.78 | STAT3 (0.67) | STAT3MAP1LC3B | |
| SCHEMBL19451277 | 0.78 | STAT3 (0.67) | STAT3MAP1LC3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4466260-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | Astrazeneca AB (SE) | 2024-11-27 | — | — | EP | disclosed |
| WO-2023139199-A1 | COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2023-07-27 | — | — | WO | disclosed |