Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 10/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 10/20 | 0.42 |
| ▸ | HTR2A | P28223 | 6/20 | 0.42 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29414342 | 0.87 | HTR2B (0.41) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL28692317 | 0.87 | HTR2B (0.41) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL30493286 | 0.84 | STAT3 (0.44) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL28650618 | 0.83 | STAT3 (0.39) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL30459956 | 0.82 | HTR2B (0.50) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL30659847 | 0.80 | PARP1 (0.49) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL660471 | 0.78 | HTR2B (0.62) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL30376302 | 0.78 | HTR2B (0.62) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| SCHEMBL30698072 | 0.78 | HTR2B (0.62) | PARP1HTR2BHTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL28593152 | 0.77 | HTR2B (0.60) | PARP1HTR2BHTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022237904-A1 | NAPHTHALENE RING-CONTAINING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | 江苏亚虹医药科技股份有限公司 | 2022-11-17 | — | — | WO | disclosed |