Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | FPR1 | P21462 | 1/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.48 |
| ▸ | CCR2 | P41597 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | VNN1 | O95497 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22470131 | 0.83 | KCNN4 (0.45) | HDAC3HDAC1HDAC2HDAC6FPR1 | |
| SCHEMBL23654370 | 0.83 | HDAC3 (0.53) | HDAC3HDAC1HDAC2HDAC6FPR1 | |
| SCHEMBL31658190 | 0.82 | HDAC3 (0.43) | HDAC3HDAC1HDAC2HDAC6FPR1 | |
| SCHEMBL5168073 | 0.80 | CCR2 (0.46) | HDAC3HDAC1HDAC2HDAC6FPR1 | |
| SCHEMBL25310148 | 0.79 | SCN9A (0.53) | HDAC3HDAC1HDAC2HDAC6OPRM1 | |
| SCHEMBL22470493 | 0.79 | HDAC3 (0.41) | HDAC3HDAC1HDAC2HDAC6FPR1 | |
| SCHEMBL28647793 | 0.78 | HDAC3 (0.48) | HDAC3HDAC1HDAC2HDAC6OPRM1 | |
| SCHEMBL28658384 | 0.78 | HDAC3 (0.40) | HDAC3HDAC1HDAC2HDAC6OPRM1 | |
| SCHEMBL26051721 | 0.77 | HDAC3 (0.46) | HDAC3HDAC1HDAC2HDAC6FPR1 | |
| SCHEMBL27853653 | 0.77 | OPRM1 (0.49) | HDAC3HDAC1HDAC2HDAC6OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113631538-A | Novel potassium channel inhibitors | 萨尼奥纳有限责任公司 | 2021-11-09 | — | — | CN | claimed |
| CN-113631538-A | Novel potassium channel inhibitors | 萨尼奥纳有限责任公司 | 2021-11-09 | — | — | CN | disclosed |