Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31360210 | 0.86 | CTSB (0.40) | FAAHTRPV1GAANPSR1ALDH1A1 | |
| SCHEMBL2036519 | 0.86 | CTSB (0.40) | FAAHTRPV1GAANPSR1ALDH1A1 | |
| SCHEMBL2030447 | 0.83 | NPSR1 (0.44) | HDAC3HDAC1HDAC2HDAC6FAAH | |
| SCHEMBL28647793 | 0.82 | HDAC3 (0.48) | HDAC3HDAC1HDAC2HDAC6FAAH | |
| SCHEMBL30344979 | 0.82 | RAB9A (0.43) | GAANPSR1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL31292775 | 0.81 | AKT1 (0.41) | FAAHTRPV1GAANPSR1ALDH1A1 | |
| SCHEMBL30749325 | 0.81 | AKT1 (0.43) | FAAHTRPV1GAANPSR1ALDH1A1 | |
| SCHEMBL14672673 | 0.81 | GAA (0.41) | HDAC3HDAC1HDAC2HDAC6FAAH | |
| SCHEMBL22470395 | 0.81 | GAA (0.35) | HDAC3HDAC1HDAC2HDAC6FAAH | |
| SCHEMBL27853653 | 0.80 | OPRM1 (0.49) | HDAC3HDAC1HDAC2HDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113631538-A | Novel potassium channel inhibitors | 萨尼奥纳有限责任公司 | 2021-11-09 | — | — | CN | claimed |
| CN-113631538-A | Novel potassium channel inhibitors | 萨尼奥纳有限责任公司 | 2021-11-09 | — | — | CN | disclosed |