SCHEMBL2865085

SCHEMBL2865085

CCCCCc1ccc(OC(=O)c2ccc(O)cc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.60
ESR1 P03372 3/20 0.60
ADRA2A P08913 2/20 0.60
ADORA3 P0DMS8 2/20 0.60
TACR2 P21452 2/20 0.60
SLC6A2 P23975 2/20 0.60
SLC6A4 P31645 2/20 0.60
SLC6A3 Q01959 2/20 0.60
CYP3A4 P08684 2/20 0.60
KDM4E B2RXH2 1/20 0.60
ALDH1A1 P00352 1/20 0.60
SHBG P04278 1/20 0.60
TP53 P04637 1/20 0.60
HSPD1 P10809 1/20 0.60
ADRB3 P13945 1/20 0.60
HTR2C P28335 1/20 0.60
HSPE1 P61604 1/20 0.60
HIF1A Q16665 1/20 0.60
TST Q16762 1/20 0.60
HSD17B10 Q99714 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28921724 1.00 LMNA (0.60) LMNAESR1ADRA2AADORA3TACR2
SCHEMBL10801643 0.99 ESR1 (0.63) LMNAESR1ADRA2AADORA3TACR2
SCHEMBL2433669 0.99 ESR1 (0.63) LMNAESR1ADRA2AADORA3TACR2
SCHEMBL9578514 0.99 ESR1 (0.63) LMNAESR1ADRA2AADORA3TACR2
SCHEMBL9735349 0.99 ESR1 (0.63) LMNAESR1ADRA2AADORA3TACR2
SCHEMBL11116193 0.95 SMN1; SMN2 (0.58) LMNAESR1ADRA2AADORA3TACR2
SCHEMBL9507965 0.95 MAPT (0.60) LMNAESR1ADRA2AADORA3TACR2
SCHEMBL3621652 0.94 THRB (0.65) LMNACYP3A4ALDH1A1THRBSMN1; SMN2
SCHEMBL7079660 0.94 THRB (0.65) LMNACYP3A4ALDH1A1THRBSMN1; SMN2
SCHEMBL8375690 0.92 THRB (0.64) LMNACYP3A4ALDH1A1THRBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3121247-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2019-10-02 EP disclosed
EP-2522649-B1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2016-04-20 EP disclosed
EP-2393902-B1 LIQUID CRYSTALLINE MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2013-10-02 EP disclosed
US-7758932-B2 Liquid crystal display device and display apparatus RICOH COMPANY, LTD. (JP) 2010-07-20 US disclosed
EP-1972676-B1 Liquid crystal alignment film composition, liquid crystal device and display apparatus RICOH KK (JP) 2010-03-10 EP disclosed
US-7658979-B2 Liquid crystal alignment film composition, liquid crystal device and display apparatus RICOH COMPANY, LTD. (JP) 2010-02-09 US disclosed
US-20080305280-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY APPARATUS RICOH COMPANY, LTD. 2008-12-11 US disclosed
US-20080231785-A1 LIQUID CRYSTAL ALIGNMENT FILM COMPOSITION, LIQUID CRYSTAL DEVICE AND DISPLAY APPARATUS RICOH COMPANY, LTD. (JP) 2008-09-25 US disclosed
EP-1972676-A1 Liquid crystal alignment film composition, liquid crystal device and display apparatus Ricoh Company, Ltd. (JP) 2008-09-24 EP disclosed
EP-0949231-B1 FLUORINE-SUBSTITUTED BENZENE DERIVATIVES, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT CHISSO CORP (JP) 2007-05-02 EP disclosed
US-4173545-A Liquid crystal with high negative dielectric anisotropy and mixtures of the same with nematic liquid crystals for improving dynamic scattering in electro-optic devices THOMSON-CSF (FR) 1979-11-06 US disclosed