Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.63 |
| ▸ | TACR2 | P21452 | 2/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.63 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | SHBG | P04278 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.63 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.63 |
| ▸ | HTR2C | P28335 | 1/20 | 0.63 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | TST | Q16762 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9578514 | 1.00 | ESR1 (0.63) | ESR1LMNAADRA2AADORA3TACR2 | |
| SCHEMBL10801643 | 1.00 | ESR1 (0.63) | ESR1LMNAADRA2AADORA3TACR2 | |
| SCHEMBL9735349 | 1.00 | ESR1 (0.63) | ESR1LMNAADRA2AADORA3TACR2 | |
| SCHEMBL2865085 | 0.99 | LMNA (0.60) | ESR1LMNAADRA2AADORA3TACR2 | |
| SCHEMBL28921724 | 0.99 | LMNA (0.60) | ESR1LMNAADRA2AADORA3TACR2 | |
| SCHEMBL9507965 | 0.96 | MAPT (0.60) | ESR1LMNAADRA2AADORA3TACR2 | |
| SCHEMBL11116193 | 0.94 | SMN1; SMN2 (0.58) | ESR1LMNAADRA2AADORA3TACR2 | |
| SCHEMBL9341873 | 0.94 | THRB (0.64) | LMNAALDH1A1CYP3A4THRBTHRA | |
| SCHEMBL8380722 | 0.94 | THRB (0.64) | LMNAALDH1A1CYP3A4THRBTHRA | |
| SCHEMBL9342490 | 0.94 | THRB (0.64) | LMNAALDH1A1CYP3A4THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3673521-B1 | DIELECTRIC LAYER COMPRISING COPOLYMER WITH MESOGENIC UNITS | PPG IND OHIO INC (US) | 2023-08-09 | — | — | EP | disclosed |
| CN-111033777-B | Dielectric layer comprising copolymer with mesogenic units | PPG工业俄亥俄公司 | 2023-08-08 | — | — | CN | disclosed |
| US-11525087-B2 | Dielectric devices and methods of fabrication | PPG INDUSTRIES OHIO, INC. (US) | 2022-12-13 | — | — | US | disclosed |
| US-20200263092-A1 | DIELECTRIC DEVICES AND METHODS OF FABRICATION | PPG INDUSTRIES OHIO, INC. | 2020-08-20 | — | — | US | disclosed |
| EP-3673521-A1 | DIELECTRIC LAYER COMPRISING COPOLYMER WITH MESOGENIC UNITS | PPG Industries Ohio, Inc. (US) | 2020-07-01 | — | — | EP | disclosed |
| CN-111033777-A | Dielectric layer comprising copolymer with mesogenic units | PPG工业俄亥俄公司 | 2020-04-17 | — | — | CN | disclosed |
| US-10619099-B2 | Dielectric devices and methods of fabrication | PPG INDUSTRIES OHIO, INC. (US) | 2020-04-14 | — | — | US | disclosed |
| WO-2019040934-A1 | DIELECTRIC LAYER COMPRISING COPOLYMER WITH MESOGENIC UNITS | PPG INDUSTRIES OHIO, INC. (US) | 2019-02-28 | — | — | WO | disclosed |
| EP-2686401-B9 | MESOGEN-CONTAINING COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2017-05-31 | — | — | EP | disclosed |
| EP-2686401-B1 | MESOGEN-CONTAINING COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2016-11-23 | — | — | EP | disclosed |
| EP-2686401-A1 | MESOGEN-CONTAINING COMPOUNDS | Transitions Optical, Inc. (US) | 2014-01-22 | — | — | EP | disclosed |
| US-8628685-B2 | Mesogen-containing compounds | TRANSITIONS OPTICAL, INC (US) | 2014-01-14 | — | — | US | disclosed |
| CN-103459553-A | Mesogen-containing compounds | TRANSITIONS OPTICAL INC | 2013-12-18 | — | — | CN | disclosed |
| WO-2012128944-A1 | MESOGEN-CONTAINING COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2012-09-27 | — | — | WO | disclosed |
| US-20110216273-A1 | MESOGEN-CONTAINING COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2011-09-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110216273-A1 | MESOGEN-CONTAINING COMPOUNDS | BMP2, MYOC, RARG | ESR1 3763/4885LMNA 1555/4885ADRA2A 878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.