Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | POLR1A | O95602 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | IL1B | P01584 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30741404 | 0.84 | MALT1 (0.46) | MALT1POLR1ATDP1ALDH1A1IL1B | |
| SCHEMBL23866592 | 0.84 | MALT1 (0.46) | MALT1POLR1ATDP1ALDH1A1IL1B | |
| SCHEMBL22519390 | 0.80 | MALT1 (0.43) | MALT1POLR1ATDP1ALDH1A1IL1B | |
| SCHEMBL23866586 | 0.80 | MALT1 (0.43) | MALT1POLR1ATDP1ALDH1A1IL1B | |
| SCHEMBL16791399 | 0.79 | MALT1 (0.43) | MALT1POLR1ATDP1ALDH1A1IL1B | |
| SCHEMBL28650884 | 0.78 | DRD2 (0.37) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7911361 | 0.78 | GLA (0.41) | MALT1TDP1ALDH1A1PDK1PDK2 | |
| SCHEMBL28645032 | 0.76 | DRD2 (0.43) | ALDH1A1 | |
| SCHEMBL22010188 | 0.74 | MALT1 (0.37) | MALT1POLR1APDK1PDK2PDK3 | |
| SCHEMBL21610612 | 0.74 | MALT1 (0.37) | MALT1POLR1APDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113631538-A | Novel potassium channel inhibitors | 萨尼奥纳有限责任公司 | 2021-11-09 | — | — | CN | claimed |
| CN-113631538-B | Novel potassium channel inhibitors | 萨尼奥纳有限责任公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-113631538-A | Novel potassium channel inhibitors | 萨尼奥纳有限责任公司 | 2021-11-09 | — | — | CN | disclosed |