Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.37 |
| ▸ | DRD1 | P21728 | 3/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | DRD5 | P21918 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28645032 | 0.89 | DRD2 (0.43) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL20851508 | 0.81 | KDM4E (0.34) | DRD2DRD3KDM4E | |
| SCHEMBL20851503 | 0.81 | KDM4E (0.34) | DRD2DRD3KDM4E | |
| SCHEMBL28650867 | 0.78 | MALT1 (0.44) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28649804 | 0.75 | CHRNB2 (0.43) | DRD2ALDH1A1 | |
| SCHEMBL8055435 | 0.74 | EPHX1 (0.43) | DRD2ALDH1A1KMT2A | |
| SCHEMBL8038051 | 0.74 | EPHX1 (0.43) | DRD2ALDH1A1KMT2A | |
| SCHEMBL11240147 | 0.72 | OPRM1 (0.46) | ALDH1A1 | |
| SCHEMBL31188523 | 0.71 | CTSL (0.59) | KDM4E | |
| SCHEMBL7904682 | 0.71 | TDP1 (0.54) | ALDH1A1CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113631538-A | Novel potassium channel inhibitors | 萨尼奥纳有限责任公司 | 2021-11-09 | — | — | CN | disclosed |