Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | LIPE | Q05469 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29758964 | 1.00 | CTSK (0.56) | CTSKACEATMHPGDNOTUM | |
| SCHEMBL18215088 | 1.00 | CTSK (0.56) | CTSKACEATMHPGDNOTUM | |
| SCHEMBL18212438 | 0.91 | NAMPT (0.51) | CTSKATMNOTUMHRH3 | |
| SCHEMBL28668564 | 0.91 | NAMPT (0.51) | CTSKATMNOTUMHRH3 | |
| SCHEMBL29758946 | 0.91 | NAMPT (0.51) | CTSKATMNOTUMHRH3 | |
| SCHEMBL9033222 | 0.89 | CTSK (0.53) | CTSKACEATMHPGDNOTUM | |
| SCHEMBL9033566 | 0.86 | CTSK (0.54) | CTSKACEATMHPGDKDM4E | |
| SCHEMBL9033559 | 0.86 | CTSK (0.54) | CTSKACEATMHPGDKDM4E | |
| SCHEMBL9527086 | 0.85 | ABHD6 (0.56) | CTSKACEATMNOTUMDRD2 | |
| SCHEMBL18215073 | 0.84 | NAMPT (0.44) | CTSKATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735088-B | Histone deacetylase inhibitors, compositions and methods of use thereof | CHDI基金会股份有限公司 | 2021-11-02 | — | — | CN | disclosed |