Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 8/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29758946 | 1.00 | NAMPT (0.51) | NAMPTCTSKDPP8DPP9DPP7 | |
| SCHEMBL18212438 | 1.00 | NAMPT (0.51) | NAMPTCTSKDPP8DPP9DPP7 | |
| SCHEMBL28650975 | 0.91 | CTSK (0.56) | CTSKATMHRH3NOTUM | |
| SCHEMBL29758964 | 0.91 | CTSK (0.56) | CTSKATMHRH3NOTUM | |
| SCHEMBL18215088 | 0.91 | CTSK (0.56) | CTSKATMHRH3NOTUM | |
| SCHEMBL6164761 | 0.82 | KMT2A (0.60) | CTSKDPP8DPP9ATMMAPK1 | |
| SCHEMBL8244870 | 0.82 | KMT2A (0.60) | CTSKDPP8DPP9ATMMAPK1 | |
| SCHEMBL10739004 | 0.81 | ACE (0.59) | — | |
| SCHEMBL27705686 | 0.81 | ACE (0.59) | — | |
| SCHEMBL31039670 | 0.80 | DRD2 (0.43) | NAMPTCTSKDPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107735088-B | Histone deacetylase inhibitors, compositions and methods of use thereof | CHDI基金会股份有限公司 | 2021-11-02 | — | — | CN | disclosed |