Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MDM4 | O15151 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30271522 | 0.87 | SMPD1 (0.31) | CTSSPOLBMAPT | |
| SCHEMBL28668938 | 0.81 | SMPD1 (0.36) | CTSSCTSKHDAC3HDAC4HDAC1 | |
| SCHEMBL28670316 | 0.80 | SMPD1 (0.33) | CTSSCTSKHDAC3HDAC4HDAC1 | |
| SCHEMBL28668469 | 0.80 | SMPD1 (0.33) | CTSSCTSKHDAC3HDAC4HDAC1 | |
| SCHEMBL28654355 | 0.75 | PTGS2 (0.33) | CTSS | |
| SCHEMBL30271516 | 0.75 | HDAC3 (0.34) | CTSSHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL30271514 | 0.75 | KCNH2 (0.34) | KMT2A | |
| SCHEMBL30271527 | 0.75 | HPGDS (0.41) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL30271528 | 0.74 | KDM4E (0.38) | POLBKDM4EKMT2AALDH1A1MAPT | |
| SCHEMBL28670645 | 0.72 | MEN1 (0.37) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |