Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 3/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28670316 | 0.89 | SMPD1 (0.33) | SMPD1POLBMAPTCTSSCTSL | |
| SCHEMBL28668469 | 0.89 | SMPD1 (0.33) | SMPD1POLBMAPTCTSSCTSL | |
| SCHEMBL28671206 | 0.86 | NTRK1 (0.37) | SMPD1POLBMAPTCTSSCTSL | |
| SCHEMBL28658947 | 0.86 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL30271522 | 0.85 | SMPD1 (0.31) | SMPD1POLBMAPTCTSSCTSL | |
| SCHEMBL28673180 | 0.85 | KDM4E (0.42) | POLBMAPTSMN1; SMN2 | |
| SCHEMBL28654355 | 0.84 | PTGS2 (0.33) | CTSSCTSLKCNH2 | |
| SCHEMBL28651067 | 0.81 | CTSS (0.36) | POLBMAPTCTSSCTSKNPC1 | |
| SCHEMBL28655200 | 0.81 | HPGD (0.43) | POLBMAPTKCNH2NPC1RAB9A | |
| SCHEMBL28676235 | 0.79 | ALDH1A1 (0.38) | SMPD1KCNH2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |