Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.56 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.56 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10036683 | 1.00 | PABPC1 (0.56) | PABPC1APOBEC3AEIF4HAPOBEC3GMAPT | |
| Bromide SCHEMBL4016614 | 0.98 | PABPC1 (0.54) | PABPC1APOBEC3AEIF4HAPOBEC3GMAPT | |
| SCHEMBL19639835 | 0.92 | PABPC1 (0.48) | PABPC1APOBEC3AEIF4HAPOBEC3GMAPT | |
| Hydrochloric Acid SCHEMBL17504837 | 0.88 | MEN1 (0.52) | PABPC1APOBEC3AEIF4HAPOBEC3GMAPT | |
| SCHEMBL19663881 | 0.87 | PABPC1 (0.44) | PABPC1APOBEC3AEIF4HAPOBEC3GMAPT | |
| SCHEMBL1305882 | 0.85 | MEN1 (0.54) | APOBEC3AAPOBEC3GMAPTLMNATERT | |
| SCHEMBL7801387 | 0.84 | PABPC1 (0.54) | PABPC1APOBEC3AEIF4HAPOBEC3GMAPT | |
| Iodide SCHEMBL3377972 | 0.83 | KDM4E (0.56) | PABPC1APOBEC3AEIF4HAPOBEC3GMAPT | |
| Bromide SCHEMBL483094 | 0.83 | MEN1 (0.52) | MAPTLMNATERTKMT2ACYP2D6 | |
| SCHEMBL29201408 | 0.83 | MEN1 (0.52) | MAPTLMNATERTKMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2098582-B1 | FUNCTIONAL ELECTRODE AND FUNCTIONAL ELECTROCHROMIC DEVICE | RICOH CO LTD (JP) | 2017-12-06 | — | — | EP | disclosed |
| US-7830584-B2 | Organic-inorganic composite material and method for producing the same, and functional electrode and functional device | RICOH COMPANY, LTD. (JP) | 2010-11-09 | — | — | US | disclosed |
| EP-2098582-A1 | ORGANIC INORGANIC COMPOSITE MATERIAL, PROCESS FOR PRODUCING THE SAME, AND FUNCTIONAL ELECTRODE AND FUNCTIONAL DEVICE | Ricoh Company, Ltd. (JP) | 2009-09-09 | — | — | EP | disclosed |
| US-20090002802-A1 | ORGANIC-INORGANIC COMPOSITE MATERIAL AND METHOD FOR PRODUCING THE SAME, AND FUNCTIONAL ELECTRODE AND FUNCTIONAL DEVICE | RICOH COMPANY, LTD. (JP) | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090002802-A1 | ORGANIC-INORGANIC COMPOSITE MATERIAL AND METHOD FOR PRODUCING THE SAME, AND FUNCTIONAL ELECTRODE AND FUNCTIONAL DEVICE | EPCAM, ILK, L1CAM | PABPC1 4573/4885APOBEC3A 2141/4885EIF4H 2800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.