Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.55 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6085939 | 0.84 | ADORA1 (0.61) | ADORA1LMNAL3MBTL1MAPK1NPSR1 | |
| SCHEMBL6085451 | 0.84 | ADORA1 (0.76) | ADORA1SERPINE1LMNAL3MBTL1MAPK1 | |
| SCHEMBL29051455 | 0.82 | IDO1 (0.80) | IDO1SERPINE1LMNAL3MBTL1MAPK1 | |
| SCHEMBL17338594 | 0.82 | LMNA (0.71) | LMNA | |
| SCHEMBL24855093 | 0.79 | SERPINE1 (0.72) | IDO1ADORA1SERPINE1LMNAPLA2G2A | |
| SCHEMBL30844603 | 0.79 | SERPINE1 (0.72) | IDO1ADORA1SERPINE1LMNAPLA2G2A | |
| SCHEMBL30040021 | 0.79 | CNR2 (0.55) | IDO1LMNACNR1CNR2 | |
| SCHEMBL28641161 | 0.79 | CNR2 (0.55) | IDO1LMNACNR1CNR2 | |
| SCHEMBL7679351 | 0.78 | ALDH1A1 (0.62) | LMNAPLA2G2A | |
| SCHEMBL28018204 | 0.78 | MEN1 (0.49) | IDO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480524-B | Alkaloid hamacanthins series derivatives, and preparation method and application thereof | 河北工业大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-113480524-A | Alkaloid hamacanthins series derivatives, and preparation method and application thereof | 河北工业大学 | 2021-10-08 | — | — | CN | disclosed |