Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.55 |
| ▸ | CNR1 | P21554 | 9/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | ICMT | O60725 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30040021 | 1.00 | CNR2 (0.55) | CNR2CNR1LMNAABCC2IDO1 | |
| SCHEMBL7385651 | 0.80 | KMT2A (0.41) | LMNAIDO1 | |
| SCHEMBL28646673 | 0.80 | LMNA (0.54) | LMNAIDO1 | |
| SCHEMBL28652105 | 0.79 | IDO1 (0.56) | CNR2CNR1LMNAIDO1 | |
| Iodide SCHEMBL27771052 | 0.74 | CNR2 (0.48) | CNR2CNR1LMNAABCC2ICMT | |
| SCHEMBL2083974 | 0.73 | PRPS1 (0.60) | CNR2CNR1LMNA | |
| SCHEMBL14136899 | 0.73 | IDO1 (0.67) | CNR2CNR1LMNAIDO1 | |
| SCHEMBL4494230 | 0.73 | CNR2 (0.61) | CNR2CNR1ICMT | |
| SCHEMBL31323947 | 0.73 | LMNA (0.64) | CNR2CNR1LMNAIDO1 | |
| SCHEMBL3862674 | 0.72 | CNR2 (0.54) | CNR2CNR1ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113480524-B | Alkaloid hamacanthins series derivatives, and preparation method and application thereof | 河北工业大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-113480524-A | Alkaloid hamacanthins series derivatives, and preparation method and application thereof | 河北工业大学 | 2021-10-08 | — | — | CN | disclosed |