Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29930196 | 0.99 | GRIN2B (0.58) | GRIN2BALDH1A1L3MBTL1GAAHSD17B10 | |
| SCHEMBL28652129 | 0.84 | CHRM2 (0.71) | GRIN2BALDH1A1L3MBTL1GAAHSD17B10 | |
| SCHEMBL28660495 | 0.82 | CHRM2 (0.72) | GRIN2BALDH1A1L3MBTL1GAAHSD17B10 | |
| SCHEMBL3067363 | 0.77 | L3MBTL1 (0.64) | ALDH1A1L3MBTL1HSD17B10MAPTRAB9A | |
| SCHEMBL8568160 | 0.76 | TP53 (0.56) | ALDH1A1L3MBTL1HSD17B10MAPTRAB9A | |
| SCHEMBL10067354 | 0.75 | LMNA (0.70) | ALDH1A1L3MBTL1GAAHSD17B10MAPT | |
| SCHEMBL10067355 | 0.75 | LMNA (0.70) | ALDH1A1L3MBTL1GAAHSD17B10MAPT | |
| SCHEMBL9776542 | 0.74 | MAPT (0.71) | ALDH1A1L3MBTL1GAAHSD17B10MAPT | |
| SCHEMBL8568247 | 0.74 | TP53 (0.58) | ALDH1A1L3MBTL1HSD17B10MAPTLMNA | |
| SCHEMBL1757508 | 0.74 | KDM4E (0.59) | ALDH1A1MAPTLMNARAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527172-B | M2 acetylcholine receptor antagonists and uses thereof | 上海交通大学医学院附属仁济医院 | 2022-10-25 | — | — | CN | disclosed |