SCHEMBL286523

SCHEMBL286523

O=Cc1cccc(O)c1Cl

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 8/20 0.61
TRIM24 O15164 1/20 0.60
TRIM33 Q9UPN9 1/20 0.60
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
TSHR P16473 2/20 0.50
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
LMNA P02545 1/20 0.46
THRB P10828 1/20 0.46
BLM P54132 1/20 0.46
TLR2 O60603 1/20 0.42
TLR1 Q15399 1/20 0.42
TLR6 Q9Y2C9 1/20 0.42
CDK4 P11802 1/20 0.42
CCND1 P24385 1/20 0.42
ALDH1A1 P00352 2/20 0.39
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29954503 1.00 ERN1 (0.61) ERN1TRIM24TRIM33CA1CA2
SCHEMBL3794351 0.83 TDP1 (0.58) ERN1TRIM24TRIM33CA1CA2
SCHEMBL16956921 0.79 TSHR (0.52) ERN1TRIM24TRIM33CA1CA2
SCHEMBL219677 0.79 ERN1 (0.54) ERN1TRIM24TRIM33MEN1KMT2A
SCHEMBL31300223 0.79 ERN1 (0.54) ERN1TRIM24TRIM33MEN1KMT2A
SCHEMBL6559485 0.77 TSHR (0.50) ERN1TRIM24TRIM33CA1CA2
SCHEMBL95211 0.76 ALDH1A1 (0.54) ERN1TRIM24TRIM33TSHRMEN1
SCHEMBL6048616 0.76 ERN1 (0.67) ERN1TRIM24TRIM33CA1CA2
SCHEMBL29407137 0.76 ERN1 (1.00) ERN1TRIM24TRIM33CA1CA2
SCHEMBL30011286 0.76 ALDH1A1 (0.54) ERN1TRIM24TRIM33TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117143126-B Afterglow type chemiluminescent molecule with controllable luminescence, nanoprobe, preparation method and application thereof 湖南大学 2026-05-19 CN claimed
CN-119528956-B BODIPY light-cage chemiluminescent molecule, nano microsphere, and synthesis method and application thereof 中南林业科技大学 2025-05-13 CN claimed
CN-119528956-A BODIPY light-cage chemiluminescent molecule, nano microsphere, and synthesis method and application thereof 中南林业科技大学 2025-02-28 CN claimed
CN-119462597-A Specific chemiluminescent probe for measuring CYP3A, preparation method and application thereof 遵义医科大学 2025-02-18 CN claimed
CN-117534662-B Norepinephrine chemiluminescence probe and preparation method and application thereof 徐州医科大学 2024-11-29 CN claimed
CN-117567369-A Sulfatase-based enzymatic chemiluminescent probe and preparation method and application thereof 中国药科大学 2024-02-20 CN claimed
CN-117534662-A Norepinephrine chemiluminescence probe and preparation method and application thereof 徐州医科大学 2024-02-09 CN claimed
CN-115417863-B Sulfur dioxide near-infrared chemiluminescent probe and preparation method and application thereof 徐州医科大学 2024-02-02 CN claimed
CN-117143126-A Afterglow type chemiluminescent molecule with controllable luminescence, nanoprobe, preparation method and application thereof 湖南大学 2023-12-01 CN claimed
CN-115340521-B Sulfur hydride chemiluminescence probe and preparation method and application thereof 徐州医科大学 2023-09-26 CN claimed
CN-115417863-A Sulfur dioxide near-infrared chemiluminescence probe and preparation method and application thereof 徐州医科大学 2022-12-02 CN claimed
CN-115340521-A Hydrogen sulfide chemiluminescent probe and preparation method and application thereof 徐州医科大学 2022-11-15 CN claimed
CN-1646460-A 2- (2, 6-dichlorophenyl) -diarylimidazoles HOFFMANN LA ROCHE (CH) 2005-07-27 CN claimed
CN-117143126-B Afterglow type chemiluminescent molecule with controllable luminescence, nanoprobe, preparation method and application thereof 湖南大学 2026-05-19 CN disclosed
US-20260132111-A1 Host-Targeted Pan-Respiratory Antiviral Small Molecule Therapeutics PROSETTA BIOSCIENCES INC (US) 2026-05-14 US disclosed
US-12552811-B2 Immunosuppressant, and preparation method therefor and use thereof ABBISKO THERAPEUTICS CO., LTD. (CN) 2026-02-17 US disclosed
EP-0172631-A1 Therapeutic agents The Boots Company PLC (GB) 1986-02-26 EP disclosed
US-4394496-A POLYEPOXEDES WITH GOOD HIGH TEMPERATURE PROPERTIES THE DOW CHEMICAL COMPANY (US) 1983-07-19 US disclosed
US-3944674-A Combating insects with o dimethoxymethylphenyl-N-methylcarbamate CIBA-GEIGY AG (CH) 1976-03-16 US disclosed
US-3933858-A INSECTICIDES CIBA-GEIGY AG (CH) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132111-A1 Host-Targeted Pan-Respiratory Antiviral Small Molecule Therapeutics NCOR1, HAVCR2, NR3C1 ERN1 942/4885TRIM24 160/4885TRIM33 128/4885
US-12552811-B2 Immunosuppressant, and preparation method therefor and use thereof CD274, PDCD1, PDCD1LG2 ERN1 3156/4885TRIM24 2426/4885TRIM33 4024/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.